The last adjustment is the calendar
At some point everything is decided. The variety is set, the site is set, the buds are dense, and the forecast says rain. Then you have exactly one decision left: when to harvest.
That's not an emergency exit but a genuine trade-off. A few days earlier costs you some ripeness. A few days later can cost you part of the harvest – and bud rot doesn't stand still, it spreads through the stand.
There is no formula. There is only the question: which is more likely – that the coming days bring ripeness, or that they bring the fungus?
And that closes the arc back to the second lesson. An early-flowering variety solves this exact problem one level earlier: it never poses the question, because it's finished in September. What you decide in autumn with the harvest knife, you could have decided in spring with the choice of variety.